Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children
نویسندگان
چکیده
Methods 12 children (mean age 6 years [range 3–10], 11 boys) were referred to a paediatric gastroenterology unit with a history of normal development followed by loss of acquired skills, including language, together with diarrhoea and abdominal pain. Children underwent gastroenterological, neurological, and developmental assessment and review of developmental records. Ileocolonoscopy and biopsy sampling, magnetic-resonance imaging (MRI), electroencephalography (EEG), and lumbar puncture were done under sedation. Barium follow-through radiography was done where possible. Biochemical, haematological, and immunological profiles were examined.
منابع مشابه
Vaccines and Autism
The first Wakefield paper In 1998, Andrew Wakefield and colleagues published a paper in The Lancet titled “Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children.” Wakefield’s hypothesis was that the MMR vaccine causes a series of events that include intestinal inflammation, loss of intestinal barrier function, entrance into the bloodstream of...
متن کاملVaccines and Autism
The first Wakefield paper In 1998, Andrew Wakefield and colleagues published a paper in The Lancet titled “Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children.” Wakefield’s hypothesis was that the MMR vaccine causes a series of events that include intestinal inflammation, loss of intestinal barrier function, entrance into the bloodstream of...
متن کامل"I've heard some things that scare me". Responding with empathy to parents' fears of vaccinations.
The Lancet's 1998 publication of "Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children" by Andrew Wakefield, et. al., positing a causal relationship between MMR vaccine and autism in children, set off a media storm and galvanized the anti-vaccine movement. In this paper, centuries-old fears of vaccination and the history of autism as a medic...
متن کاملRetraction--Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children.
Following the judgment of the UK General Medical Council’s Fitness to Practise Panel on Jan 28, 2010, it has become clear that several elements of the 1998 paper by Wakefield et al are incorrect, contrary to the findings of an earlier investigation. In particular, the claims in the original paper that children were “consecutively referred” and that investigations were “approved” by the local et...
متن کاملIleal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children.
BACKGROUND We investigated a consecutive series of children with chronic enterocolitis and regressive developmental disorder. METHODS 12 children (mean age 6 years [range 3-10], 11 boys) were referred to a paediatric gastroenterology unit with a history of normal development followed by loss of acquired skills, including language, together with diarrhoea and abdominal pain. Children underwent...
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